Serum levels of CA-125 in patients with endometriosis: a preliminary report

Seven out of 8 patients with endometriosis demonstrated levels of CA-125 antigen above 35 U/ml. None of 15 patients with other benign gynecologic diagnoses demonstrated elevated levels. This antigen has been proposed as a tumor marker for epithelial carcinoma and other gynecologic neoplasms. However...

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Veröffentlicht in:	Fertility and sterility 1986-06, Vol.45 (6), p.876-878
Hauptverfasser:	Giudice, Linda C., Jacobs, Allan, Pineda, Jorge, Elliott Bell, C., Lippmann, Lynne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens, Neoplasm - analysis Antigens, Surface - analysis Antigens, Tumor-Associated, Carbohydrate Biological and medical sciences Carcinoma - immunology Diagnosis, Differential Endometriosis - diagnosis Endometriosis - immunology Endometriosis - pathology Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Leiomyoma - immunology Medical sciences Middle Aged Non tumoral diseases Osteitis Deformans - immunology Ovarian Cysts - immunology Ovarian Neoplasms - immunology Prognosis Uterine Neoplasms - immunology
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Zusammenfassung:	Seven out of 8 patients with endometriosis demonstrated levels of CA-125 antigen above 35 U/ml. None of 15 patients with other benign gynecologic diagnoses demonstrated elevated levels. This antigen has been proposed as a tumor marker for epithelial carcinoma and other gynecologic neoplasms. However, it cannot be used to differentiate clinically between cancer and endometriosis.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/S0015-0282(16)49409-4