Gene Therapy--So Near and Yet So Far Away

Research into gene therapy suggests that genes transferred into cultured cells often work well, but foreign genes are often inactive when they are transferred into live animals by methods similar to those hoped to be used on humans.

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Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1986-05, Vol.232 (4752), p.824-825
1. Verfasser:	Marx, Jean L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Deaminase - deficiency Adenosine Deaminase - genetics Analysis Anderson, W. French Animals Biological and medical sciences Biotechnology Bone Marrow Bone marrow cells Cultured cells Forecasts and trends Fundamental and applied biological sciences. Psychology Gene therapy Genes Genetic Diseases, Inborn - genetics Genetic Diseases, Inborn - therapy Genetic Engineering Genetic research Genetic Vectors Genetics Haplorhini Health. Pharmaceutical industry Hock, Randy Humans Industrial applications and implications. Economical aspects Messenger RNA Mice Miller, A. Dusty Orkin, Stuart Research News Stem cells Transplants & implants Williams, David
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Research into gene therapy suggests that genes transferred into cultured cells often work well, but foreign genes are often inactive when they are transferred into live animals by methods similar to those hoped to be used on humans.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.3085217