Ciprofloxacin resistant Serratia marcescens endocarditis as a complication of non-Hodgkin's lymphoma

We report a case of endocarditis caused by a ciprofloxacin-resistant strain of Serratia marcescens in a 50-year-old female neutropenic patient with non-Hodgkin's lymphoma which occurred while receiving ciprofloxacin prophylaxis. She made poor progress on first line therapy with azlocillin and g...

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Veröffentlicht in:	The Journal of infection 1994-07, Vol.29 (1), p.73-76
Hauptverfasser:	Körner, R.J., Nicol, A., Reeves, D.S., MacGowan, A.P., Hows, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Azlocillin - administration & dosage Azlocillin - therapeutic use Bacterial diseases Bacterial endocarditis, myocarditis and pericarditis. Bacterial diseases of the aorta, limb vessels and lymphatic vessels Biological and medical sciences Ciprofloxacin - administration & dosage Ciprofloxacin - pharmacology Drug Resistance, Microbial Endocarditis, Bacterial - etiology Female Gentamicins - administration & dosage Gentamicins - therapeutic use Human bacterial diseases Humans Infectious diseases Infusions, Intravenous Lymphoma, Non-Hodgkin - complications Medical sciences Middle Aged Serratia Infections - etiology Serratia marcescens Serratia marcescens - drug effects
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Zusammenfassung:	We report a case of endocarditis caused by a ciprofloxacin-resistant strain of Serratia marcescens in a 50-year-old female neutropenic patient with non-Hodgkin's lymphoma which occurred while receiving ciprofloxacin prophylaxis. She made poor progress on first line therapy with azlocillin and gentamicin by bolus injection t.d.s. The infection was finally eliminated by a regimen of continuous infusion of azlocillin and once daily gentamicin.
ISSN:	0163-4453 1532-2742
DOI:	10.1016/S0163-4453(94)95141-1