Characterization of 3,5,3′-Triiodo-L-thyronine Transport into Hepatocytes Isolated from Juvenile Rainbow Trout ( Oncorhynchus mykiss), and Comparison with L-Thyroxine Transport

Uptake of 3,5,3′-triiodo-L-thyronine (T 3) by isolated trout hepatocytes was characterized after 40 sec incubation of cells in a balanced salts medium containing [ 125]T 3, and compared to L-thyroxine (T 4) uptake (Riley and Eales, Gen. Comp. Endocrinol. 90, 31-42, 1993). T 3 uptake resembled T 4 up...

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Veröffentlicht in:	General and comparative endocrinology 1994-08, Vol.95 (2), p.301-309
Hauptverfasser:	Riley, W.W., Eales, J.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Endocytosis - drug effects Energy Metabolism - physiology Fundamental and applied biological sciences. Psychology Hormones. Regulation Hydrogen-Ion Concentration In Vitro Techniques Kinetics Liver - cytology Liver - metabolism Molecular Conformation Oncorhynchus mykiss - metabolism Protein Binding - drug effects Sodium - physiology Sulfhydryl Compounds - pharmacology Temperature Thyroid. Parathyroid. Ultimobranchial body Thyroxine - metabolism Triiodothyronine - metabolism Vertebrates: endocrinology
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Zusammenfassung:	Uptake of 3,5,3′-triiodo-L-thyronine (T 3) by isolated trout hepatocytes was characterized after 40 sec incubation of cells in a balanced salts medium containing [ 125]T 3, and compared to L-thyroxine (T 4) uptake (Riley and Eales, Gen. Comp. Endocrinol. 90, 31-42, 1993). T 3 uptake resembled T 4 uptake in several ways. There was a small (
ISSN:	0016-6480 1095-6840
DOI:	10.1006/gcen.1994.1127