Elevated serum concentrations of CA-125 in patients with advanced endometriosis

CA-125 is a high-molecular-weight glycoprotein that is expressed on the cell surface of some derivatives of embryonic coelomic epithelium. Based on results of an immunoradiometric assay developed to detect CA-125 in peripheral blood, 82% of patients with ovarian cancer and35U/ml. Immunocytochemical...

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Veröffentlicht in:	Fertility and sterility 1986-05, Vol.45 (5), p.630-634
Hauptverfasser:	Barbieri, Robert L., Niloff, Jonathan M., Bast, Robert C., Schaetzl, Elena, Kistner, Robert W., Knapp, Robert C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antigens, Neoplasm - analysis Antigens, Tumor-Associated, Carbohydrate Applied sciences Biological and medical sciences Chronic Disease Endometriosis - immunology Endometriosis - pathology Exact sciences and technology Female Female genital diseases Gynecology. Andrology. Obstetrics Histocytochemistry Humans Immunoassay - methods Leiomyoma - immunology Medical sciences Middle Aged Neoplasm Staging Non tumoral diseases Other techniques and industries Pelvic Inflammatory Disease - immunology Uterine Neoplasms - immunology Uterine Neoplasms - pathology
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Zusammenfassung:	CA-125 is a high-molecular-weight glycoprotein that is expressed on the cell surface of some derivatives of embryonic coelomic epithelium. Based on results of an immunoradiometric assay developed to detect CA-125 in peripheral blood, 82% of patients with ovarian cancer and35U/ml. Immunocytochemical techniques demonstrated the presence of CA-125 on the cell surface of endometriotic lesions.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/S0015-0282(16)49333-7