Identification of a cellular transcription factor involved in E1A trans-activation

We have employed a gel assay to detect a transcription factor in nuclear extracts of adenovirus-infected cells that interacts with the adenovirus E2 promoter, an E1A inducible promoter. Binding of the factor to the promoter protected sequences between −33 and −74 from DNAase cleavage in a footprint...

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Veröffentlicht in:	Cell 1986-04, Vol.45 (2), p.219-228
Hauptverfasser:	Kovesdi, Imre, Reichel, Ronald, Nevins, Joseph R.
Format:	Artikel
Sprache:	eng
Schlagworte:	adenovirus Adenovirus Early Proteins Adenoviruses, Human - genetics Base Sequence Binding Sites Biological and medical sciences Fundamental and applied biological sciences. Psychology Gene Expression Regulation HeLa Cells Humans Models, Genetic Molecular and cellular biology Molecular genetics Oncogene Proteins, Viral - biosynthesis Oncogene Proteins, Viral - genetics Promoter Regions, Genetic Transcription Factors - genetics Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing
Online-Zugang:	Volltext
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