Effects of endotoxin and cytokines on lipid metabolism

Effects of endotoxin and cytokines on lipid metabolism

Endotoxin, via cytokines, induces marked changes in lipid metabolism: serum VLDL increases, whereas the effect on LDL levels varies among species. The increase in VLDL is caused by stimulation of hepatic VLDL secretion or inhibition of clearance, or both. These alterations can be deleterious or bene...

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Veröffentlicht in:Current opinion in lipidology 1994-06, Vol.5 (3), p.207-215
Hauptverfasser: Hardardóttir, I, Grünfeld, C, Feingold, K R
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cholesterol - metabolism
Cytokines - pharmacology
Endotoxins - pharmacology
Lipid Metabolism
Triglycerides - metabolism
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Zusammenfassung:Endotoxin, via cytokines, induces marked changes in lipid metabolism: serum VLDL increases, whereas the effect on LDL levels varies among species. The increase in VLDL is caused by stimulation of hepatic VLDL secretion or inhibition of clearance, or both. These alterations can be deleterious or beneficial effects.
ISSN:0957-9672
DOI:10.1097/00041433-199405030-00008