Effect of profound hypothermia on leukocytes and platelets
Seventeen patients who underwent aortic arch replacement were subjected to profound hypothermia and circulatory arrest. At maximum cooling, platelet count dropped from 184 +/- 122 to 37 +/- 30 thousand per microliter, and the total leukocytic count fell from 6.27 +/- 4.0 to 1.47 +/- 0.6 thousand per...
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| Veröffentlicht in: | Annals of clinical and laboratory science 1986-03, Vol.16 (2), p.130-133 |
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| creator | SHENAQ, S. A YAWN, D. H SALEEM, A JOSWIAK, R CRAWFORD, E. S |
| description | Seventeen patients who underwent aortic arch replacement were subjected to profound hypothermia and circulatory arrest. At maximum cooling, platelet count dropped from 184 +/- 122 to 37 +/- 30 thousand per microliter, and the total leukocytic count fell from 6.27 +/- 4.0 to 1.47 +/- 0.6 thousand per microliter. The thrombocytopenia was partially reversed with rewarming. The total white cell count consistently returned to precooling values or higher (10.5 +/- 4.0). The mechanism for this cold induced phenomenon is not well understood. |
| format | Article |
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S</creatorcontrib><title>Effect of profound hypothermia on leukocytes and platelets</title><title>Annals of clinical and laboratory science</title><addtitle>Ann Clin Lab Sci</addtitle><description>Seventeen patients who underwent aortic arch replacement were subjected to profound hypothermia and circulatory arrest. At maximum cooling, platelet count dropped from 184 +/- 122 to 37 +/- 30 thousand per microliter, and the total leukocytic count fell from 6.27 +/- 4.0 to 1.47 +/- 0.6 thousand per microliter. The thrombocytopenia was partially reversed with rewarming. The total white cell count consistently returned to precooling values or higher (10.5 +/- 4.0). The mechanism for this cold induced phenomenon is not well understood.</description><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Aorta, Thoracic - surgery</subject><subject>Aortic Aneurysm - surgery</subject><subject>Biological and medical sciences</subject><subject>Blood Platelets - cytology</subject><subject>Hot Temperature</subject><subject>Humans</subject><subject>Hypothermia - blood</subject><subject>Leukocyte Count</subject><subject>Leukocytes - cytology</subject><subject>Medical sciences</subject><subject>Platelet Count</subject><subject>Thoracic and cardiovascular surgery. 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Cell therapy and gene therapy</topic><topic>Aorta, Thoracic - surgery</topic><topic>Aortic Aneurysm - surgery</topic><topic>Biological and medical sciences</topic><topic>Blood Platelets - cytology</topic><topic>Hot Temperature</topic><topic>Humans</topic><topic>Hypothermia - blood</topic><topic>Leukocyte Count</topic><topic>Leukocytes - cytology</topic><topic>Medical sciences</topic><topic>Platelet Count</topic><topic>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SHENAQ, S. A</creatorcontrib><creatorcontrib>YAWN, D. H</creatorcontrib><creatorcontrib>SALEEM, A</creatorcontrib><creatorcontrib>JOSWIAK, R</creatorcontrib><creatorcontrib>CRAWFORD, E. 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S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of profound hypothermia on leukocytes and platelets</atitle><jtitle>Annals of clinical and laboratory science</jtitle><addtitle>Ann Clin Lab Sci</addtitle><date>1986-03-01</date><risdate>1986</risdate><volume>16</volume><issue>2</issue><spage>130</spage><epage>133</epage><pages>130-133</pages><issn>0091-7370</issn><eissn>1550-8080</eissn><coden>ACLSCP</coden><abstract>Seventeen patients who underwent aortic arch replacement were subjected to profound hypothermia and circulatory arrest. At maximum cooling, platelet count dropped from 184 +/- 122 to 37 +/- 30 thousand per microliter, and the total leukocytic count fell from 6.27 +/- 4.0 to 1.47 +/- 0.6 thousand per microliter. The thrombocytopenia was partially reversed with rewarming. The total white cell count consistently returned to precooling values or higher (10.5 +/- 4.0). The mechanism for this cold induced phenomenon is not well understood.</abstract><cop>Philadelphia, PA</cop><pub>Institute for Clinical Science</pub><pmid>3963733</pmid><tpages>4</tpages></addata></record> |
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| ispartof | Annals of clinical and laboratory science, 1986-03, Vol.16 (2), p.130-133 |
| issn | 0091-7370 1550-8080 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76785263 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Anesthesia Anesthesia depending on type of surgery Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Aorta, Thoracic - surgery Aortic Aneurysm - surgery Biological and medical sciences Blood Platelets - cytology Hot Temperature Humans Hypothermia - blood Leukocyte Count Leukocytes - cytology Medical sciences Platelet Count Thoracic and cardiovascular surgery. Cardiopulmonary bypass |
| title | Effect of profound hypothermia on leukocytes and platelets |
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