The effect of very low radiation doses on the human bladder carcinoma cell line RT112

Human RT112 cells were exposed to single doses of X-rays (0.05–5 Gy), and cell survival was measured using a Dynamic Microscopic Imaging Processing Scanner (DMIPS) with which individual cells can be located in tissue-culture flasks, their positions recorded, and after an appropriate incubation time the recorded positions revisited to allow the accurate scoring of survivors. The response over the X-ray dose range 1–5 Gy showed a good fit to a Linear-Quadratic (LQ) model. For X-ray doses