Oral Glucose Tolerance Test Using a Continuous Blood Sampling Technique for Analysis of the Blood Glucose Curve

Blood glucose levels were continuously monitored in 70 subjects during a 75g orla glucose tolerance test (OGTT). Subjects were divided into normal (N=15), borderline (N=31), diabetes with fasting glucose levels below 140mg/dl (DM1) (N=15) and diabetes with levels above 140mg/dl (DM2) (N=9). Three patterns of blood glucose curves were observed in each subject group; domed, biphasic and upward. The frequency of blood glocose patterns in each class of glucose tolerance group was as follows: in the normal group; domed 33.3%, biphasic 66.7%; in the borderline group; domed 67.7%, biphasic 29.0%, upward 3.2%; in the DM1 group; domed 66.7%, biphasic 13.3%, upward 20.0%; in the DM2 group; domed 77.8%, upward 22.2%. The frequency of patients with a biphasic pattern was significantly higher in the normal group than in the other groups. In the borderline group, almost all patients with a biphasic pattern were young or middle aged (