Satellite DNA in the three C-bands of an unusual mouse marker chromosome: A model of chromosomal evolution

A marker chromosome in the stemline of a new murine cell line is described on the basis of different stainings and in situ hybridization. The marker was characterized originally by three C-bands, one from each centromeric region of the three chromosomes constituting the marker. In the course of stem...

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Veröffentlicht in:	Experimental cell research 1986, Vol.164 (1), p.256-260
Hauptverfasser:	Árnason, Úlfur, Manolova, Yanka, Manolov, George, Bregula, Urszula, Levan, Albert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Evolution Cell Line Chromosome Banding Chromosomes - analysis Chromosomes - ultrastructure Cytogenetics DNA, Satellite - analysis Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Heterochromatin - analysis Human Karyotyping Mice Nucleic Acid Hybridization
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Zusammenfassung:	A marker chromosome in the stemline of a new murine cell line is described on the basis of different stainings and in situ hybridization. The marker was characterized originally by three C-bands, one from each centromeric region of the three chromosomes constituting the marker. In the course of stemline evolution, two of the C-bands have been lost and the marker has developed into a monocentric chromosome, phenotypically and functionally normal.
ISSN:	0014-4827 1090-2422
DOI:	10.1016/0014-4827(86)90473-8