Effect of hypercapnia on fluid filtration rate during forward and reverse perfusion of isolated rabbit lungs

Fluid filtration rate (FFR) was measured under predominantly zone-three conditions in isolated rabbit lung perfused at constant flow. During forward and reverse perfusion, alveolar hypercapnia significantly increased mean pulmonary artery pressure but did not change FFR. We conclude that the pulmona...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Critical care medicine 1986-04, Vol.14 (4), p.285-287
Hauptverfasser:	DE LEN, ROBERTO SÁNCHEZ, BRAJKOVICH, IMPERIA, ZABNER, JOSEPH, MARTINEZ-RUIZ, RICARDO, ANGELI, SIMN
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Carbon Dioxide - blood Emergency and intensive respiratory care Hydrogen-Ion Concentration Hypercapnia - metabolism Hypercapnia - physiopathology Intensive care medicine Lung - metabolism Medical sciences Oxygen - blood Pulmonary Circulation Pulmonary Wedge Pressure Rabbits Space life sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Fluid filtration rate (FFR) was measured under predominantly zone-three conditions in isolated rabbit lung perfused at constant flow. During forward and reverse perfusion, alveolar hypercapnia significantly increased mean pulmonary artery pressure but did not change FFR. We conclude that the pulmonary vasoconstriction induced by alveolar hypercapnia occurs on both arterial and venular sides of the pulmonary circulation.
ISSN:	0090-3493 1530-0293
DOI:	10.1097/00003246-198604000-00007