GLYCOTHIOHEXIDE α, A NOVEL ANTIBIOTIC PRODUCED BY "Sebekia" sp., LL-14E605: II. ISOLATION AND PHYSICAL-CHEMICAL CHARACTERIZATION

Glycothiohexide α was recovered from the fermentation broth of a "Sebekia" sp. by mixed solvent extraction, selective precipitation and adsorption chromatography on Diaion HP-20. The amount of glycothiohexide α present in the crude preparation was enriched by photolysis. Purification of gl...

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Veröffentlicht in:Journal of antibiotics 1994/08/25, Vol.47(8), pp.894-900
Hauptverfasser: NORTHCOTE, P. T., WILLIAMS, D., MANNING, J. K., BORDERS, D. B., MAIESE, W. M., LEE, M. D.
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Sprache:eng
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Zusammenfassung:Glycothiohexide α was recovered from the fermentation broth of a "Sebekia" sp. by mixed solvent extraction, selective precipitation and adsorption chromatography on Diaion HP-20. The amount of glycothiohexide α present in the crude preparation was enriched by photolysis. Purification of glycothiohexide α was accomplished by repetitive countercurrent Chromatography.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.47.894