Glutamate receptor phosphorylation and synaptic plasticity

Glutamate receptor phosphorylation and synaptic plasticity

The recent findings that glutamate receptors are phosphorylated and functionally modulated by protein kinases has provided evidence that phosphorylation of these receptors may play a critical role in mechanisms of synaptic plasticity.

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Bibliographische Detailangaben
Veröffentlicht in:Current opinion in neurobiology 1994-06, Vol.4 (3), p.383-388
Hauptverfasser: Roche, Katherine W., Tingley, Whittemore G., Huganir, Richard L.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Humans
Neuronal Plasticity
Phosphoric Monoester Hydrolases - physiology
Phosphorylation
Protein Kinases - physiology
Receptors, AMPA - metabolism
Receptors, Glutamate - metabolism
Receptors, Kainic Acid - metabolism
Receptors, N-Methyl-D-Aspartate - metabolism
Synapses - physiology
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Beschreibung
Zusammenfassung:The recent findings that glutamate receptors are phosphorylated and functionally modulated by protein kinases has provided evidence that phosphorylation of these receptors may play a critical role in mechanisms of synaptic plasticity.
ISSN:0959-4388
1873-6882
DOI:10.1016/0959-4388(94)90100-7