General high-performance liquid chromatographic procedures for the rapid screening of natural and synthetic corticosteroids

A study of a multiple high-performance liquid chromatographic procedure for the separation of 30 different corticosteroids is described. Normal- and reversed-phase general methods operating in a wide polarity range have been developed for the rapid screening of multicomponent mixtures. The complemen...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 1994-06, Vol.12 (6), p.805-810
Hauptverfasser:	Valvo, L., Paris, A., Savella, A.L., Gallinella, B., Signoretti, E.Cirani
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - analysis Adrenal Cortex Hormones - chemical synthesis Analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods corticosteroid mixtures screening General pharmacology Medical sciences Natural and synthetic corticosteroids normal-phase HPLC Pharmacology. Drug treatments reversed-phase HPLC
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Zusammenfassung:	A study of a multiple high-performance liquid chromatographic procedure for the separation of 30 different corticosteroids is described. Normal- and reversed-phase general methods operating in a wide polarity range have been developed for the rapid screening of multicomponent mixtures. The complementary application of both normal- and reversed-phase methods could permit clarification of uncertainty deriving from analyses performed by only one method.
ISSN:	0731-7085 1873-264X
DOI:	10.1016/0731-7085(93)E0029-M