Isolation and sequencing of a cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase from Toxoplasma gondii

Isolation and sequencing of a cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase from Toxoplasma gondii

A hypoxanthine-guanine phosphoribosyltransferase-encoding gene ( HGPRT) from Toxoplasma gondii has been isolated and sequenced. The identity of the enzyme was determined by sequence comparison and complementation in a mutant Escherichia coli.

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Bibliographische Detailangaben
Veröffentlicht in:Gene 1994-09, Vol.147 (1), p.153-154
Hauptverfasser: Vasanthakumar, Geetha, van Ginkel, Sabrina, Parish, Gregory
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
complementation
DNA, Complementary - genetics
Genes, Protozoan
HGPRT-deficient Escherichia coli
Hypoxanthine Phosphoribosyltransferase - genetics
molecular cloning
Molecular Sequence Data
pathogen
purine pathway
Recombinant DNA
Toxoplasma - genetics
Toxoplasma gondii
λZAPII
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Beschreibung
Zusammenfassung:A hypoxanthine-guanine phosphoribosyltransferase-encoding gene ( HGPRT) from Toxoplasma gondii has been isolated and sequenced. The identity of the enzyme was determined by sequence comparison and complementation in a mutant Escherichia coli.
ISSN:0378-1119
1879-0038
DOI:10.1016/0378-1119(94)90058-2