Negative and positive effects of intracerebroventricular scopolamine on memory in mice undergoing passive avoidance and escape tests

The effects of intracerebroventricular administration of scopolamine on memory and learning in the conscious, freely moving mouse were evaluated using step-down passive avoidance and water maze tests. A new technique was used that allows convenient injection into the cerebral ventricles without dist...

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Veröffentlicht in:	Brain research bulletin 1994, Vol.34 (4), p.375-380
Hauptverfasser:	Nakajima, Masaharu, Inui, Akio, Miura, Masaki, Hirosue, Yoshiaki, Okita, Minoru, Himori, Norio, Baba, Shigeaki, Kasuga, Masato
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Avoidance Learning - drug effects Behavioral psychophysiology Biological and medical sciences Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology ICV injection system Injections, Intraventricular Male Memory Memory - drug effects Mice Mice, Inbred Strains Motor Activity - drug effects Mouse Neurotransmission and behavior Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Scopolamine Scopolamine - administration & dosage Scopolamine - pharmacology Space Perception - drug effects
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