Endothelial desquamating activity of rat synthetic fibrinopeptide b and its analogues “in vivo” : Identification of responsible sequence

The endothelial desquamating activity of the synthetic rat fibrinopeptide B (ATTDSDKVDLSIAR-OH), and its analogues was studied “in vivo” after intravenous administration to rats. Rat fibrinopeptide B (FPB) caused a significant increase in the count of circulating endothelial cell carcasses at the do...

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Veröffentlicht in:	Thrombosis research 1994-05, Vol.74 (4), p.409-418
Hauptverfasser:	Šimák, Jan, Holada, Karel, Zábrodský, Vladimir, Komalik, František
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding Sites - physiology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system endothelial cells Endothelium, Vascular - drug effects Female fibrinogen fibrinopeptide B Fibrinopeptide B - chemistry Fibrinopeptide B - pharmacology Keratolytic Agents - chemistry Keratolytic Agents - pharmacology Medical sciences Miscellaneous Molecular Sequence Data Rats Rats, Wistar Sequence Homology, Amino Acid Species Specificity thrombin vessel wall
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