Homologous pairing of DNA molecules by ustilago rec1 protein is promoted by sequences of Z-DNA

Plasmids containing Z-DNA stretches can be paired and linked by combined action of Ustilago rec1 protein and topoisomerase. The product formed is a hemicatenated dimer in which two DNA rings are topologically intertwined at a region of homology. Superhelicity governs the reaction. Formation of linke...

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Veröffentlicht in:	Cell 1986-02, Vol.44 (4), p.545-554
Hauptverfasser:	Kmiec, Eric B., Holloman, William K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-Antibody Complex Applied sciences Base Sequence Biological and medical sciences DNA, Superhelical - genetics DNA, Superhelical - immunology Exact sciences and technology Exodeoxyribonuclease V Fundamental and applied biological sciences. Psychology Fungal Proteins - physiology Genic rearrangement. Recombination. Transposable element Hydrogen Bonding Molecular and cellular biology Molecular genetics Nucleic Acid Conformation Other techniques and industries Plasmids Recombination, Genetic Sequence Homology, Nucleic Acid Structure-Activity Relationship Ustilago - genetics
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