Heteroduplex stabilities in highly repetitive DNA: An hypothesis for the polymorphism of Plasmodium parasite antigenic response
Codon repeats encountered in DNA sequences may formally lead to several double-stranded structures of similar stabilities. This is observed in the highly repetitive sequences of some Plasmodium antigens (S-antigen, CS proteins). It is postulated that gene recombination may occur via various heterodu...
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| Veröffentlicht in: | FEBS letters 1986-03, Vol.197 (1), p.5-8 |
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| creator | Dodin, Guy |
| description | Codon repeats encountered in DNA sequences may formally lead to several double-stranded structures of similar stabilities. This is observed in the highly repetitive sequences of some
Plasmodium antigens (S-antigen, CS proteins). It is postulated that gene recombination may occur via various heteroduplex molecules thus leading to antigenic polymorphism of
Plasmodium parasites. |
| doi_str_mv | 10.1016/0014-5793(86)80286-1 |
| format | Article |
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Plasmodium antigens (S-antigen, CS proteins). It is postulated that gene recombination may occur via various heteroduplex molecules thus leading to antigenic polymorphism of
Plasmodium parasites.</description><subject>Animals</subject><subject>Antigens, Protozoan - genetics</subject><subject>Biochemistry. Physiology. Immunology. Molecular biology</subject><subject>Biological and medical sciences</subject><subject>Biological Evolution</subject><subject>DNA - genetics</subject><subject>Fundamental and applied biological sciences. 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This is observed in the highly repetitive sequences of some
Plasmodium antigens (S-antigen, CS proteins). It is postulated that gene recombination may occur via various heteroduplex molecules thus leading to antigenic polymorphism of
Plasmodium parasites.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>3512307</pmid><doi>10.1016/0014-5793(86)80286-1</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | FEBS letters, 1986-03, Vol.197 (1), p.5-8 |
| issn | 0014-5793 1873-3468 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76707127 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via ScienceDirect (Elsevier); Alma/SFX Local Collection |
| subjects | Animals Antigens, Protozoan - genetics Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences Biological Evolution DNA - genetics Fundamental and applied biological sciences. Psychology Malaria Antigenic polymorphism (Plasmodium) Repetitive sequence Models, Biological Nucleic Acid Heteroduplexes Plasmodium Plasmodium - genetics Plasmodium - immunology Plasmodium falciparum - genetics Plasmodium falciparum - immunology Polymorphism, Genetic Protozoa Recombination, Genetic Repetitive Sequences, Nucleic Acid |
| title | Heteroduplex stabilities in highly repetitive DNA: An hypothesis for the polymorphism of Plasmodium parasite antigenic response |
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