SEROEPIDEMIOLOGY OF HEPATITIS B VIRUS IN THE PHILIPPINES

Hepatitis B virus markers were studied in 2,842 Philippine rural subjects from four villages in 1979–1982. The prevalence of hepatitis B surface antigen (HBsAg) and all markers for hepatitis B virus averaged 12% and 58%, respectively, in these rural populations. It is estimated that five million Fil...

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Veröffentlicht in:American journal of epidemiology 1986-03, Vol.123 (3), p.473-480
Hauptverfasser: LINGAO, AUGUSTO L., DOMINGO, ERNESTO O., WEST, SHEILA, REYES, CESAR M., GASMEN, SERGIO, VITERBO, GEORGE, TIU, EDITH, LANSANG, MARY ANN
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Sprache:eng
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Zusammenfassung:Hepatitis B virus markers were studied in 2,842 Philippine rural subjects from four villages in 1979–1982. The prevalence of hepatitis B surface antigen (HBsAg) and all markers for hepatitis B virus averaged 12% and 58%, respectively, in these rural populations. It is estimated that five million Filipinos are HBsAg positive. The rural age-specific HBsAg prevalence shows an “early peak” (In persons 3–4-years-old) In two communities and a “late peak” (In persons 30–40-years-old) In the other two communities. Family studies suggest that the prevalence of HBsAg and hepatitis B e antigen (HBeAg) among parents of the young children in an “early peak” and a “late peak” village cannot fully account for the difference in the patterns of prevalence of all markers, or the HBsAg marker. Horizontal intrafamilial and extrafamilial transmission may also be significant. Further research is needed on risk factors for hepatitis B virus infection.
ISSN:0002-9262
1476-6256
DOI:10.1093/oxfordjournals.aje.a114262