Immunoassay reagents for psychoactive drugs. Part 4. Quantitative determination of amitriptyline and nortriptyline by fluorescence polarization immunoassay

Methods for the quantitative determination of amitriptyline and nortriptyline by fluorescence polarization immunoassay (FPIA) is described. One immunoassay allows for the accurate quantification of amitriptyline in the presence of nortriptyline while the second immunoassay allows for the accurate qu...

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Veröffentlicht in:	Therapeutic drug monitoring 1994-06, Vol.16 (3), p.298-311
Hauptverfasser:	Adamczyk, M, Fishpaugh, J R, Harrington, C A, Hartter, D E, Vanderbilt, A S, Orsulak, P, Akers, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amitriptyline - blood Amitriptyline - immunology Animals Chromatography, High Pressure Liquid Cross Reactions Fluorescence Polarization Immunoassay Fluorescent Dyes Humans Indicators and Reagents Nortriptyline - blood Nortriptyline - immunology Psychotropic Drugs - blood Rabbits - immunology Solvents
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Beschreibung
Zusammenfassung:	Methods for the quantitative determination of amitriptyline and nortriptyline by fluorescence polarization immunoassay (FPIA) is described. One immunoassay allows for the accurate quantification of amitriptyline in the presence of nortriptyline while the second immunoassay allows for the accurate quantification of nortriptyline in the presence of amitriptyline.
ISSN:	0163-4356
DOI:	10.1097/00007691-199406000-00012