Indole ring binds to 7-methylguanine base by π-π stacking interaction: Crystal structure of 7-methylguanosine 5'-monophosphate-tryptamine complex

Strong π-π stacking interaction between the indole ring and 7-methylguanine base was shown by X-ray crystal analysis of the 7-methylguanosine 5'-monophosphate-tryptamine complex. This interaction appears to be strengthened by the attachment of ribose and phosphate groups to the base.

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Veröffentlicht in:FEBS letters 1986-01, Vol.195 (1), p.57-60
Hauptverfasser: Kamiichi, Katsuhisa, Danshita, Masaya, Minamino, Naoko, Doi, Mitsunobu, Ishida, Toshimasa, Inoue, Masatoshi
Format: Artikel
Sprache:eng
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Zusammenfassung:Strong π-π stacking interaction between the indole ring and 7-methylguanine base was shown by X-ray crystal analysis of the 7-methylguanosine 5'-monophosphate-tryptamine complex. This interaction appears to be strengthened by the attachment of ribose and phosphate groups to the base.
ISSN:0014-5793
1873-3468
DOI:10.1016/0014-5793(86)80129-6