Development of Myelopathy Before Herpes Zoster Rash in a Patient with AIDS

We describe the case of a patient with AIDS who developed progressive myelopathy due to varicella-zoster virus 2 months before the appearance of skin lesions typical of herpes zoster. Varicella-zoster virus was isolated from his CSF. Therapy with acyclovir failed to control his neurological complica...

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Veröffentlicht in:	Clinical infectious diseases 1994-05, Vol.18 (5), p.810-812
Hauptverfasser:	Gómez-Tortosa, E., Gadea, I., Gegúndez, M. I., Esteban, A., Rábano, J., Fernández-Guerrero, M. L., Soriano, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS AIDS-Related Opportunistic Infections - microbiology AIDS/HIV Cerebrospinal Fluid - microbiology Exanthema Herpes zoster Herpes Zoster - complications Herpesvirus 3, Human - isolation & purification Humans Infections Lesions Male Myelitis Myelitis - cerebrospinal fluid Myelitis - etiology Myelitis - microbiology Skin Skin - pathology Spinal cord diseases Varicella zoster encephalitis varicella-zoster virus Viruses
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Zusammenfassung:	We describe the case of a patient with AIDS who developed progressive myelopathy due to varicella-zoster virus 2 months before the appearance of skin lesions typical of herpes zoster. Varicella-zoster virus was isolated from his CSF. Therapy with acyclovir failed to control his neurological complications despite its in vitro efficacy against the isolates.
ISSN:	1058-4838 1537-6591
DOI:	10.1093/clinids/18.5.810