Differential Apomorphine Effects

Two dose levels of apomorphine were used with the tail-flick assay. A low dose of apomorphine significantly increased tail-flick latency, whereas a high dose significantly decreased tail-flick latency. Such differential effects have bearing on the reported complex interaction between the dopamine an...

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Veröffentlicht in:	Behavioral neuroscience 1985-08, Vol.99 (4), p.776-777
Hauptverfasser:	Wesler, Lee S, Frey, Allan H
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesia Analgesics Animal Animals Apomorphine Apomorphine - pharmacology Biological and medical sciences Brain - drug effects Brain - physiopathology Dopamine Dopamine - physiology Drug Dosages Endorphins Endorphins - physiology Male Medical sciences Neuropharmacology Pain - physiopathology Pharmacology. Drug treatments Rats Rats, Inbred Strains
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Zusammenfassung:	Two dose levels of apomorphine were used with the tail-flick assay. A low dose of apomorphine significantly increased tail-flick latency, whereas a high dose significantly decreased tail-flick latency. Such differential effects have bearing on the reported complex interaction between the dopamine and endorphin systems in the brain.
ISSN:	0735-7044 1939-0084
DOI:	10.1037/0735-7044.99.4.776