Testosterone metabolism in the uropygial gland of the quail

The metabolism of testosterone in the uropygial gland of the quail principally results in the production of 17α, 5β derivatives. Moreover, an unusually small amount of testosterone is converted to 5α-dihydrotestosterone. These results question the role played by intracellular 5α-reduction in the res...

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Veröffentlicht in:	Steroids 1985-05, Vol.45 (5), p.391-401
Hauptverfasser:	Floch, J.Y., Morfin, R., Picart, D., Daniel, J.Y., Floch, H.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism Animals Biological and medical sciences Dihydrotestosterone - biosynthesis Dihydrotestosterone - isolation & purification Epitestosterone - biosynthesis Exocrine Glands - metabolism Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Male NADP - metabolism Quail - metabolism Steroid hormones. Cholecalciferol derivatives Testosterone - metabolism Vertebrates: endocrinology
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Beschreibung
Zusammenfassung:	The metabolism of testosterone in the uropygial gland of the quail principally results in the production of 17α, 5β derivatives. Moreover, an unusually small amount of testosterone is converted to 5α-dihydrotestosterone. These results question the role played by intracellular 5α-reduction in the response of the gland to testosterone stimulation.
ISSN:	0039-128X 1878-5867
DOI:	10.1016/0039-128X(85)90004-2