Evaluation of radiocolloids as thrombus imaging agents. Effect of particle size on thrombus uptake

Thrombus uptake values of several 99mTc labeled radiocolloids determined using an experimental rodent model of deep venous thrombosis were correlated with particle size distributions. The thrombus uptake values increased with increasing mean particle size. The 99mTc-tin colloid had the highest throm...

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Veröffentlicht in:	International journal of nuclear medicine & biology 1985, Vol.12 (5), p.375-380
Hauptverfasser:	Rosenthal, Steven N., Bardfeld, Philip A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Miscellaneous. Technology Particle Size Radionuclide investigations Rats Rats, Inbred Strains Technetium Technetium Compounds Technetium Tc 99m Sulfur Colloid Thrombophlebitis - diagnosis Tin Tin Compounds Tissue Distribution
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Zusammenfassung:	Thrombus uptake values of several 99mTc labeled radiocolloids determined using an experimental rodent model of deep venous thrombosis were correlated with particle size distributions. The thrombus uptake values increased with increasing mean particle size. The 99mTc-tin colloid had the highest thrombus uptake value of any of the colloids used in this study.
ISSN:	0047-0740
DOI:	10.1016/S0047-0740(85)80007-3