Punctate porokeratotic keratoderma-its occurrence with internal neoplasia

Summary Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, acuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted b...

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Veröffentlicht in:Clinical and experimental dermatology 1994-03, Vol.19 (2), p.139-141
Hauptverfasser: BIANCHI, L., ORLANDI, A., IRACI, S., SPAGNOLI, L.G., NINI, G.
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Sprache:eng
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Zusammenfassung:Summary Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, acuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 19732. A patient with a 3‐month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed.
ISSN:0307-6938
1365-2230
DOI:10.1111/j.1365-2230.1994.tb01142.x