Punctate porokeratotic keratoderma-its occurrence with internal neoplasia
Summary Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, acuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted b...
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Veröffentlicht in: | Clinical and experimental dermatology 1994-03, Vol.19 (2), p.139-141 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Summary
Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, acuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 19732. A patient with a 3‐month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed. |
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ISSN: | 0307-6938 1365-2230 |
DOI: | 10.1111/j.1365-2230.1994.tb01142.x |