The Effect of Propranolol and Thioridazine on Positive and Negative Symptoms of Schizophrenia

Patients with chronic schizophrenia were treated with either propranolol (640 mg daily) or thioridazine (400 mg daily). In a double-blind study lasting five weeks, propranolol was superior to thioridazine on both psychiatrists' and nurses' ratings. Significant improvements were noted with...

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Veröffentlicht in:	British journal of psychiatry 1985-12, Vol.147 (6), p.623-630
Hauptverfasser:	Eccleston, D., Fairbairn, A. F., Hassanyeh, F., McClelland, H. A., Stephens, D. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Blood Pressure - drug effects Clinical Trials as Topic Double-Blind Method Female Humans Male Middle Aged Propranolol - therapeutic use Psychiatric Status Rating Scales Pulse - drug effects Schizophrenia - drug therapy Schizophrenia - physiopathology Schizophrenic Psychology Thioridazine - therapeutic use Time Factors
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Beschreibung
Zusammenfassung:	Patients with chronic schizophrenia were treated with either propranolol (640 mg daily) or thioridazine (400 mg daily). In a double-blind study lasting five weeks, propranolol was superior to thioridazine on both psychiatrists' and nurses' ratings. Significant improvements were noted with propranolol in both positive (Type I) and negative (Type II) symptoms.
ISSN:	0007-1250 1472-1465
DOI:	10.1192/bjp.147.6.623