Neurobiology. Catching the culprit prion

Prions are the infectious agents of certain neurological diseases, replicate like viruses and seem to be devoid of nucleic acid genomes. The latest insight into the conversion of PrPc into PrPSc is discussed.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1994-08, Vol.370 (6489), p.419-420
Hauptverfasser:	Beyreuther, K, Masters, C L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell-Free System Disease Endopeptidases - metabolism Humans Infections Nervous system Nucleic acids Prion Diseases - transmission Prions - chemistry Prions - metabolism Protein Conformation
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Prions are the infectious agents of certain neurological diseases, replicate like viruses and seem to be devoid of nucleic acid genomes. The latest insight into the conversion of PrPc into PrPSc is discussed.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/370419a0