Homomorphism on a physical system of the Hodgkin-Huxley equations for ion conductance in nerve

A homomorphism on a physical system of the Hodgkin-Huxley equations for ion conductance in nerve is derived. It is pointed out that a homomorphism can correct the Cole-Moore discrepancy in delay of conductance for voltage clamp data with initial hyperpolarization. The voltage dependence of the rate...

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Veröffentlicht in:	Journal of theoretical biology 1985-12, Vol.117 (4), p.509-527
1. Verfasser:	Strandberg, M.W.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Biological and medical sciences Electric Conductivity Fundamental and applied biological sciences. Psychology Isolated neuron and nerve. Neuroglia Mathematics Membrane Potentials Nerve Fibers - physiology Neural Conduction Potassium - physiology Sodium - physiology Vertebrates: nervous system and sense organs
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Zusammenfassung:	A homomorphism on a physical system of the Hodgkin-Huxley equations for ion conductance in nerve is derived. It is pointed out that a homomorphism can correct the Cole-Moore discrepancy in delay of conductance for voltage clamp data with initial hyperpolarization. The voltage dependence of the rate constants can also be removed. Curves are presented to compare the representation of the nerve conductances by the Hodgkin-Huxley equations and the new homomorphism.
ISSN:	0022-5193 1095-8541
DOI:	10.1016/S0022-5193(85)80235-6