A yeast artificial chromosome contig on mouse chromosome 11 encompassing the nu locus

Mutations at the nude locus disrupt the homing process of T cell progenitor cells to the thymic rudiment, a key aspect of T cell differentiation. Here, we map the nude locus to a set of overlapping yeast artificial chromosomes (YAC) clones covering a genetic interval of about 0.5 centi Morgan on mou...

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Veröffentlicht in:European journal of immunology 1994-07, Vol.24 (7), p.1721-1723
Hauptverfasser: Nehls, Michael, Lüno, Karsten, Schorpp, Michael, Krause, Sabine, Matysiak‐Scholze, Uta, Prokop, Christa‐Maria, Hedrich, Hans J., Boehm, Thomas
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container_end_page 1723
container_issue 7
container_start_page 1721
container_title European journal of immunology
container_volume 24
creator Nehls, Michael
Lüno, Karsten
Schorpp, Michael
Krause, Sabine
Matysiak‐Scholze, Uta
Prokop, Christa‐Maria
Hedrich, Hans J.
Boehm, Thomas
description Mutations at the nude locus disrupt the homing process of T cell progenitor cells to the thymic rudiment, a key aspect of T cell differentiation. Here, we map the nude locus to a set of overlapping yeast artificial chromosomes (YAC) clones covering a genetic interval of about 0.5 centi Morgan on mouse chromosome 11. These results provide a suitable starting point to molecularly clone the nude gene.
doi_str_mv 10.1002/eji.1830240742
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ispartof European journal of immunology, 1994-07, Vol.24 (7), p.1721-1723
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Animals
Base Sequence
Biological and medical sciences
Chromosome Mapping - veterinary
Chromosomes, Artificial, Yeast
Crosses, Genetic
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Genetic Markers
Immune deficiency
Immunobiology
Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Nude - genetics
Molecular Sequence Data
Mouse
Mutation
Nude
YAC
title A yeast artificial chromosome contig on mouse chromosome 11 encompassing the nu locus
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