Cretinism after weekly dosing with levothyroxine for treatment of congenital hypothyroidism
An 11-month-old infant was treated elsewhere for congenital hypothyroidism with weekly doses of levothyroxine. The infant had cardinal features of cretinism including poor growth, delayed skeletal maturation, and mental retardation. Treatment of such infants with weekly doses of levothyroxine cannot...
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Veröffentlicht in: | The Journal of pediatrics 1994-07, Vol.125 (1), p.147-149 |
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creator | Rivkees, Scott A. Hardin, Dana S. |
description | An 11-month-old infant was treated elsewhere for congenital hypothyroidism with weekly doses of levothyroxine. The infant had cardinal features of cretinism including poor growth, delayed skeletal maturation, and mental retardation. Treatment of such infants with weekly doses of levothyroxine cannot be justified. (J P
EDIATR 1994;125:147-9) |
doi_str_mv | 10.1016/S0022-3476(94)70142-3 |
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EDIATR 1994;125:147-9)</description><subject>Biological and medical sciences</subject><subject>Bronchiolitis Obliterans - etiology</subject><subject>Congenital Hypothyroidism - etiology</subject><subject>Drug Administration Schedule</subject><subject>Endocrinopathies</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>Hypothyroidism - complications</subject><subject>Hypothyroidism - drug therapy</subject><subject>Infant</subject><subject>Medical sciences</subject><subject>Non tumoral diseases. Target tissue resistance. Benign neoplasms</subject><subject>Thyroid. Thyroid axis (diseases)</subject><subject>Thyroxine - administration & dosage</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtvEzEQgC0EakPhJ1TyAaFyWOpXvPYJVVF5SJU40J44WI49blx27WA7Lfn33TRRrpxGo_nm9SF0TslnSqi8_EUIYx0XvbzQ4lNPqJiyV2hGie47qTh_jWZH5BS9rfWBEKIFISfoRBFGeyln6PeiQIsp1hHb0KDgJ4A_wxb7XGO6x0-xrfAAj7mttiX_iwlwyAW3AraNkBrOAbuc7iHFZge82q73ZPTTxHfoTbBDhfeHeIbuvl7fLr53Nz-__Vhc3XSOK9067YVfEq-11E4pIJIFyp3yQjsx3cnkXNk5X2opiXdLJgPwIDVVXvOeBcL4Gfq4n7su-e8GajNjrA6GwSbIm2p6Oe93D0_gfA-6kmstEMy6xNGWraHE7KSaF6lmZ8xoYV6kGj71nR8WbJYj-GPXweJU_3Co2-rsEIpNLtYjJqhUPdMT9mWPwSTjMUIx1UVIDnws4JrxOf7nkGfFzJR5</recordid><startdate>19940701</startdate><enddate>19940701</enddate><creator>Rivkees, Scott A.</creator><creator>Hardin, Dana S.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19940701</creationdate><title>Cretinism after weekly dosing with levothyroxine for treatment of congenital hypothyroidism</title><author>Rivkees, Scott A. ; Hardin, Dana S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-9d4db0d9969c88e062f13c8d49c48022658a53b9660dcb26fe3f6918d9372f023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Biological and medical sciences</topic><topic>Bronchiolitis Obliterans - etiology</topic><topic>Congenital Hypothyroidism - etiology</topic><topic>Drug Administration Schedule</topic><topic>Endocrinopathies</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Humans</topic><topic>Hypothyroidism - complications</topic><topic>Hypothyroidism - drug therapy</topic><topic>Infant</topic><topic>Medical sciences</topic><topic>Non tumoral diseases. Target tissue resistance. Benign neoplasms</topic><topic>Thyroid. Thyroid axis (diseases)</topic><topic>Thyroxine - administration & dosage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rivkees, Scott A.</creatorcontrib><creatorcontrib>Hardin, Dana S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rivkees, Scott A.</au><au>Hardin, Dana S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cretinism after weekly dosing with levothyroxine for treatment of congenital hypothyroidism</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>1994-07-01</date><risdate>1994</risdate><volume>125</volume><issue>1</issue><spage>147</spage><epage>149</epage><pages>147-149</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><coden>JOPDAB</coden><abstract>An 11-month-old infant was treated elsewhere for congenital hypothyroidism with weekly doses of levothyroxine. The infant had cardinal features of cretinism including poor growth, delayed skeletal maturation, and mental retardation. Treatment of such infants with weekly doses of levothyroxine cannot be justified. (J P
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subjects | Biological and medical sciences Bronchiolitis Obliterans - etiology Congenital Hypothyroidism - etiology Drug Administration Schedule Endocrinopathies Fatal Outcome Female Humans Hypothyroidism - complications Hypothyroidism - drug therapy Infant Medical sciences Non tumoral diseases. Target tissue resistance. Benign neoplasms Thyroid. Thyroid axis (diseases) Thyroxine - administration & dosage |
title | Cretinism after weekly dosing with levothyroxine for treatment of congenital hypothyroidism |
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