Theophylline reduces the response to nasal challenge with antigen

A nasal challenge model of allergic rhinitis was used to determine if pretreatment with oral theophylline reduces histamine release in vivo. Ten subjects were entered into a double-blind, cross-over trial. The results showed that both the physiologic response (sneezing) (p = 0.02) and the amount of...

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Bibliographische Detailangaben

Veröffentlicht in:	The American journal of medicine 1985-12, Vol.79 (6), p.43-47
Hauptverfasser:	Naclerio, Robert M., Bartenfelder, Denise, Proud, David, Togias, Alkis G., Meyers, Deborah A., Kagey-Sobotka, Anne, Norman, Philip S., Lichtenstein, Lawrence M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bronchial Provocation Tests Double-Blind Method Female Histamine Release - drug effects Humans Kinins - analysis Male Peptide Hydrolases - analysis Rhinitis - physiopathology Sneezing - drug effects Theophylline - pharmacology
Online-Zugang:	Volltext
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