Correlation of clinical response (PANSS) and plasma levels of haloperidol and reduced haloperidol in schizophrenia

1. The authors attempted to correlate plasma concentrations in H/rH and clinical efficacy from 8 schizophrenic patients (DSM III R) on H. 2. No significant correlations were found between H, rH plasma levels and positive and negative subscale for each patient. 3. The authors observed an opposite evo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 1994-03, Vol.18 (2), p.347-353
Hauptverfasser:	Leroux, Jean-Marc, Elia, Edvick, Jacquet, Michele, Pommery, Jean, Levron, Jean-Claude, Bouhours, Philippe, ERB, Francoise, Sechter, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Chromatography, High Pressure Liquid clinical response Female haloperidol Haloperidol - analogs & derivatives Haloperidol - blood Haloperidol - therapeutic use haloperidol decanoate Humans Male Medical sciences Middle Aged Neuropharmacology oral haloperidol Pharmacology. Drug treatments plasma concentration Psychiatric Status Rating Scales Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology reduced haloperidol Schizophrenia, Paranoid - drug therapy Schizophrenic Psychology Spectrophotometry, Ultraviolet
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	1. The authors attempted to correlate plasma concentrations in H/rH and clinical efficacy from 8 schizophrenic patients (DSM III R) on H. 2. No significant correlations were found between H, rH plasma levels and positive and negative subscale for each patient. 3. The authors observed an opposite evolution concerning the mean results between plasma concentrations and PANSS total score.
ISSN:	0278-5846 1878-4216
DOI:	10.1016/0278-5846(94)90066-3