Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain

Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to br...

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Veröffentlicht in:Magnetic resonance in medicine 1994-04, Vol.31 (4), p.454-460
Hauptverfasser: Davis, D., Ulatowski, J., Eleff, S., Izuta, M., Mori, S., Shungu, D., van Zijl, P. C. M.
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container_end_page 460
container_issue 4
container_start_page 454
container_title Magnetic resonance in medicine
container_volume 31
creator Davis, D.
Ulatowski, J.
Eleff, S.
Izuta, M.
Mori, S.
Shungu, D.
van Zijl, P. C. M.
description Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.
doi_str_mv 10.1002/mrm.1910310416
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source MEDLINE; Wiley Journals
subjects Animals
Biological and medical sciences
Body Water - physiology
Brain - physiopathology
Brain Ischemia - physiopathology
Cats
cerebral blood flow
Diffusion
Investigative techniques, diagnostic techniques (general aspects)
ischemia-reperfusion
Magnetic Resonance Spectroscopy
Medical sciences
Monitoring, Physiologic
Nervous system
NMR spectroscopy
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Rats
title Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain
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