Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain
Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to br...
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Veröffentlicht in: | Magnetic resonance in medicine 1994-04, Vol.31 (4), p.454-460 |
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container_title | Magnetic resonance in medicine |
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creator | Davis, D. Ulatowski, J. Eleff, S. Izuta, M. Mori, S. Shungu, D. van Zijl, P. C. M. |
description | Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis. |
doi_str_mv | 10.1002/mrm.1910310416 |
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The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.</description><identifier>ISSN: 0740-3194</identifier><identifier>EISSN: 1522-2594</identifier><identifier>DOI: 10.1002/mrm.1910310416</identifier><identifier>PMID: 8208123</identifier><identifier>CODEN: MRMEEN</identifier><language>eng</language><publisher>Baltimore: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animals ; Biological and medical sciences ; Body Water - physiology ; Brain - physiopathology ; Brain Ischemia - physiopathology ; Cats ; cerebral blood flow ; Diffusion ; Investigative techniques, diagnostic techniques (general aspects) ; ischemia-reperfusion ; Magnetic Resonance Spectroscopy ; Medical sciences ; Monitoring, Physiologic ; Nervous system ; NMR spectroscopy ; Pathology. Cytology. Biochemistry. Spectrometry. 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C. M.</creatorcontrib><title>Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain</title><title>Magnetic resonance in medicine</title><addtitle>Magn. Reson. Med</addtitle><description>Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Body Water - physiology</subject><subject>Brain - physiopathology</subject><subject>Brain Ischemia - physiopathology</subject><subject>Cats</subject><subject>cerebral blood flow</subject><subject>Diffusion</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>ischemia-reperfusion</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Monitoring, Physiologic</subject><subject>Nervous system</subject><subject>NMR spectroscopy</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Rats</subject><issn>0740-3194</issn><issn>1522-2594</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1v1DAQxS1EVZbClRuSD4hbtv5M4iOqYIFui1SB4GZNnHFrmjhbO6H0vyfbXS3ixOkd5vfezDxCXnG25IyJ0z71S244k5wpXj4hC66FKIQ26ilZsEqxQnKjnpHnOf9kjBlTqWNyXAtWcyEX5PYKNqGl_RDDOKQQr-ngqbuBeI2ZhkjvYcRE2-D9lMMQqRvQ--ACxjHTdnp0JPyFKYemQxqyu8E-wNbqYKQQW5pmbRKE-IIceegyvtzrCfn24f3Xs4_F-svq09m7deE0E2XRGOZaVkmPyrXalBqVVw6hrjVUoGctvWqgrer5MQXe1JpppxvNlC8BmTwhb3e5mzTcTZhH2893YddBxGHKtiq11IJXM7jcgS4NOSf0dpNCD-nBcma37dq5Xfu33dnwep88NT22B3xf5zx_s59DdtD5BNGFfMCkMbUQ2xizw-5Dhw__WWovri7-OaHYeUMe8ffBC-nWlpWstP1-ubKfL89X8gdfWyP_ANLTo14</recordid><startdate>199404</startdate><enddate>199404</enddate><creator>Davis, D.</creator><creator>Ulatowski, J.</creator><creator>Eleff, S.</creator><creator>Izuta, M.</creator><creator>Mori, S.</creator><creator>Shungu, D.</creator><creator>van Zijl, P. 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M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5026-b90cd073fe4cd5965e4f4cea885a7a5a886f4bad781944af98505c5b504f6ae03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Body Water - physiology</topic><topic>Brain - physiopathology</topic><topic>Brain Ischemia - physiopathology</topic><topic>Cats</topic><topic>cerebral blood flow</topic><topic>Diffusion</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>ischemia-reperfusion</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>Monitoring, Physiologic</topic><topic>Nervous system</topic><topic>NMR spectroscopy</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Rats</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Davis, D.</creatorcontrib><creatorcontrib>Ulatowski, J.</creatorcontrib><creatorcontrib>Eleff, S.</creatorcontrib><creatorcontrib>Izuta, M.</creatorcontrib><creatorcontrib>Mori, S.</creatorcontrib><creatorcontrib>Shungu, D.</creatorcontrib><creatorcontrib>van Zijl, P. C. 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subjects | Animals Biological and medical sciences Body Water - physiology Brain - physiopathology Brain Ischemia - physiopathology Cats cerebral blood flow Diffusion Investigative techniques, diagnostic techniques (general aspects) ischemia-reperfusion Magnetic Resonance Spectroscopy Medical sciences Monitoring, Physiologic Nervous system NMR spectroscopy Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Rats |
title | Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain |
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