Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain

Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to br...

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Veröffentlicht in:	Magnetic resonance in medicine 1994-04, Vol.31 (4), p.454-460
Hauptverfasser:	Davis, D., Ulatowski, J., Eleff, S., Izuta, M., Mori, S., Shungu, D., van Zijl, P. C. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Water - physiology Brain - physiopathology Brain Ischemia - physiopathology Cats cerebral blood flow Diffusion Investigative techniques, diagnostic techniques (general aspects) ischemia-reperfusion Magnetic Resonance Spectroscopy Medical sciences Monitoring, Physiologic Nervous system NMR spectroscopy Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Rats
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Beschreibung
Zusammenfassung:	Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.
ISSN:	0740-3194 1522-2594
DOI:	10.1002/mrm.1910310416