In-vitro susceptibility of mycobacteria to ciprofloxacin
Two hundred and seventy-six strains of mycobacteria were tested for susceptibility to ciprofloxacin (Bay 0 9867), a 4-quinolone antimicrobial agent. Most strains of Mycobacterium tuberculosis, Myco. fortuitum, Myco. kansasii, Myco. marinum and Myco. xenopi were sensitive to minimum inhibitory concen...
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| Veröffentlicht in: | Journal of antimicrobial chemotherapy 1985-11, Vol.16 (5), p.575-580 |
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| container_end_page | 580 |
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| container_title | Journal of antimicrobial chemotherapy |
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| creator | Collins, C. H. Uttley, Anne H. C. |
| description | Two hundred and seventy-six strains of mycobacteria were tested for susceptibility to ciprofloxacin (Bay 0 9867), a 4-quinolone antimicrobial agent. Most strains of Mycobacterium tuberculosis, Myco. fortuitum, Myco. kansasii, Myco. marinum and Myco. xenopi were sensitive to minimum inhibitory concentrations (MICs) of 0·78–1·56 mg/l, equivalent to resistance ratios of 1 or 2. Most strains of Myco. avium-intracellulare and Myco. chelonei required MICs of 12·5 mg/l or more, giving resistance ratios of 8. |
| doi_str_mv | 10.1093/jac/16.5.575 |
| format | Article |
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H. ; Uttley, Anne H. C.</creator><creatorcontrib>Collins, C. H. ; Uttley, Anne H. C.</creatorcontrib><description>Two hundred and seventy-six strains of mycobacteria were tested for susceptibility to ciprofloxacin (Bay 0 9867), a 4-quinolone antimicrobial agent. Most strains of Mycobacterium tuberculosis, Myco. fortuitum, Myco. kansasii, Myco. marinum and Myco. xenopi were sensitive to minimum inhibitory concentrations (MICs) of 0·78–1·56 mg/l, equivalent to resistance ratios of 1 or 2. Most strains of Myco. avium-intracellulare and Myco. chelonei required MICs of 12·5 mg/l or more, giving resistance ratios of 8.</description><identifier>ISSN: 0305-7453</identifier><identifier>EISSN: 1460-2091</identifier><identifier>DOI: 10.1093/jac/16.5.575</identifier><identifier>PMID: 2934361</identifier><identifier>CODEN: JACHDX</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Anti-Bacterial Agents - pharmacology ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Ciprofloxacin ; Culture Media ; Drug Resistance, Microbial ; Medical sciences ; Microbial Sensitivity Tests ; Mycobacterium ; Mycobacterium - drug effects ; Mycobacterium Infections - microbiology ; Mycobacterium tuberculosis - drug effects ; Pharmacology. 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C.</creatorcontrib><title>In-vitro susceptibility of mycobacteria to ciprofloxacin</title><title>Journal of antimicrobial chemotherapy</title><addtitle>J Antimicrob Chemother</addtitle><description>Two hundred and seventy-six strains of mycobacteria were tested for susceptibility to ciprofloxacin (Bay 0 9867), a 4-quinolone antimicrobial agent. Most strains of Mycobacterium tuberculosis, Myco. fortuitum, Myco. kansasii, Myco. marinum and Myco. xenopi were sensitive to minimum inhibitory concentrations (MICs) of 0·78–1·56 mg/l, equivalent to resistance ratios of 1 or 2. Most strains of Myco. avium-intracellulare and Myco. chelonei required MICs of 12·5 mg/l or more, giving resistance ratios of 8.</description><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Ciprofloxacin</subject><subject>Culture Media</subject><subject>Drug Resistance, Microbial</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Mycobacterium</subject><subject>Mycobacterium - drug effects</subject><subject>Mycobacterium Infections - microbiology</subject><subject>Mycobacterium tuberculosis - drug effects</subject><subject>Pharmacology. 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Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Ciprofloxacin</topic><topic>Culture Media</topic><topic>Drug Resistance, Microbial</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Mycobacterium</topic><topic>Mycobacterium - drug effects</topic><topic>Mycobacterium Infections - microbiology</topic><topic>Mycobacterium tuberculosis - drug effects</topic><topic>Pharmacology. Drug treatments</topic><topic>Quinolines - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Collins, C. H.</creatorcontrib><creatorcontrib>Uttley, Anne H. 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| fulltext | fulltext |
| identifier | ISSN: 0305-7453 |
| ispartof | Journal of antimicrobial chemotherapy, 1985-11, Vol.16 (5), p.575-580 |
| issn | 0305-7453 1460-2091 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals Digital Archive Legacy |
| subjects | Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Ciprofloxacin Culture Media Drug Resistance, Microbial Medical sciences Microbial Sensitivity Tests Mycobacterium Mycobacterium - drug effects Mycobacterium Infections - microbiology Mycobacterium tuberculosis - drug effects Pharmacology. Drug treatments Quinolines - pharmacology |
| title | In-vitro susceptibility of mycobacteria to ciprofloxacin |
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