Bone remodelling and orthodontics

odontics is based on the predictable remodelling of bone surrounding and supporting the teeth in response to stimuli generated or brought about by orthodontic appliances. Progress in orthodontics depends on further insight into bone remodelling which will make prognosis and relapse more predictable as well. This is a review of a series of relevant clinical and experimental observations which show that it is possible to gain insight into factors underlying bone remodelling and thereby expand the physiological basis of orthodontics. The regeneration of lost and the generation of congenitally missing segments of the mandible are used as illustrations.