Long-term intraindividual cholesterol variability: Natural course and adverse impact on morbidity and mortality—the Framingham Study

Long-term intraindividual cholesterol variability: Natural course and adverse impact on morbidity and mortality—the Framingham Study

We examined intraindividual variability in serum TC in 2912 men and women having TC measured at each of biennial examinations 2 through 7 of the FHS. RMSE described variability around the linear slope of an individual's TC during the baseline decade. Average biennial difference ±SD was +3.7 ± 6...

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Veröffentlicht in:The American heart journal 1994-06, Vol.127 (6), p.1607-1614
Hauptverfasser: Kreger, Bernard E., Odell, Patricia M., D'Agostino, Ralph B., Wilson, Peter F.W.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Cardiology. Vascular system
Cardiovascular Diseases - blood
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - mortality
Cholesterol - blood
Coronary heart disease
Female
Follow-Up Studies
Heart
Humans
Incidence
Linear Models
Male
Massachusetts - epidemiology
Medical sciences
Middle Aged
Proportional Hazards Models
Risk Factors
Sex Distribution
Time Factors
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Zusammenfassung:We examined intraindividual variability in serum TC in 2912 men and women having TC measured at each of biennial examinations 2 through 7 of the FHS. RMSE described variability around the linear slope of an individual's TC during the baseline decade. Average biennial difference ±SD was +3.7 ± 6.7 mg/dl in men, +6.6 ±8.8 mg/dl in women. RMSE was
ISSN:0002-8703
1097-6744
DOI:10.1016/0002-8703(94)90393-X