Conserved Linkage of Early Growth Response 4, Annexin 4, and Transforming Growth Factor α on Mouse Chromosome 6
The mouse genes encoding early growth response 4 (Egr4), annexin IV (Anx4), and transforming growth factor a (Tgfa) have been mapped to a linkage group on mouse chromosome 6 that is conserved on human chromosome 2p11-p13. The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa an...
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| Veröffentlicht in: | Genomics (San Diego, Calif.) Calif.), 1994-01, Vol.19 (2), p.388-390 |
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| container_title | Genomics (San Diego, Calif.) |
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| creator | Barrow, Lon L. Simin, Karl Jones, Julie M. Lee, David C. Meisler, Miriam H. |
| description | The mouse genes encoding early growth response 4 (Egr4), annexin IV (Anx4), and transforming growth factor a (Tgfa) have been mapped to a linkage group on mouse chromosome 6 that is conserved on human chromosome 2p11-p13. The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa and 1/215 recombinants between these genes and Egr4 . The genes are located approximately 2 cM distal to mnd2, a mouse mutation causing neuromuscular disease. The results demonstrate that mnd2 is located at an internal position within this conserved linkage group. |
| doi_str_mv | 10.1006/geno.1994.1078 |
| format | Article |
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The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa and 1/215 recombinants between these genes and Egr4 . The genes are located approximately 2 cM distal to mnd2, a mouse mutation causing neuromuscular disease. The results demonstrate that mnd2 is located at an internal position within this conserved linkage group.</description><identifier>ISSN: 0888-7543</identifier><identifier>EISSN: 1089-8646</identifier><identifier>DOI: 10.1006/geno.1994.1078</identifier><identifier>PMID: 8188273</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Animals ; Annexin A4 - genetics ; Biological and medical sciences ; Chromosome Mapping ; Classical genetics, quantitative genetics, hybrids ; Fundamental and applied biological sciences. Psychology ; Genes ; Genetic Linkage ; Genetics of eukaryotes. 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The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa and 1/215 recombinants between these genes and Egr4 . The genes are located approximately 2 cM distal to mnd2, a mouse mutation causing neuromuscular disease. The results demonstrate that mnd2 is located at an internal position within this conserved linkage group.</description><subject>Animals</subject><subject>Annexin A4 - genetics</subject><subject>Biological and medical sciences</subject><subject>Chromosome Mapping</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes</subject><subject>Genetic Linkage</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>Humans</subject><subject>Mice - genetics</subject><subject>Neuromuscular Diseases - genetics</subject><subject>Recombination, Genetic</subject><subject>Transcription Factors - genetics</subject><subject>Transforming Growth Factor alpha - genetics</subject><subject>Vertebrata</subject><subject>Zinc Fingers</subject><issn>0888-7543</issn><issn>1089-8646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1uEzEUhS0EKqGwZYfkBWLFBP-Nf5ZV1BakICRU1pbjuZO6nbGDPQn0sXgRngmPErpDrHyt-92je89B6DUlS0qI_LCFmJbUGFG_Sj9BC0q0abQU8ilaEK11o1rBn6MXpdwRQgzX7Aydaao1U3yBdqsUC-QDdHgd4r3bAk49vnR5eMDXOf2YbvFXKLsZwuI9vogRfoY4ly52-Ca7WPqUxxC3f_Er56eU8e9fOEX8Oe3r4Oo2pzGVNAKWL9Gz3g0FXp3ec_Tt6vJm9bFZf7n-tLpYN15wMzWtqDdRwplXgrUbzTsQIFi_ka7bcCM5YVT20ErqhGe-c4oq0XaKaiLbeiQ_R--Ourucvu-hTHYMxcMwuAh1KaukMIwY81-QSkOrIq_g8gj6nErJ0NtdDqPLD5YSO2dh5yzsnIWds6gDb07K-80I3SN-Mr_23576rng39NVMH8ojxg1TlLQV00cMql2HANkWHyB66EIGP9kuhX9t8Ad_36Pb</recordid><startdate>19940115</startdate><enddate>19940115</enddate><creator>Barrow, Lon L.</creator><creator>Simin, Karl</creator><creator>Jones, Julie M.</creator><creator>Lee, David C.</creator><creator>Meisler, Miriam H.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19940115</creationdate><title>Conserved Linkage of Early Growth Response 4, Annexin 4, and Transforming Growth Factor α on Mouse Chromosome 6</title><author>Barrow, Lon L. ; Simin, Karl ; Jones, Julie M. ; Lee, David C. ; Meisler, Miriam H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-541991032c7425b83de4e42fb6adb39630216fe561a4c2cda71745d7180659383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Animals</topic><topic>Annexin A4 - genetics</topic><topic>Biological and medical sciences</topic><topic>Chromosome Mapping</topic><topic>Classical genetics, quantitative genetics, hybrids</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes</topic><topic>Genetic Linkage</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>Humans</topic><topic>Mice - genetics</topic><topic>Neuromuscular Diseases - genetics</topic><topic>Recombination, Genetic</topic><topic>Transcription Factors - genetics</topic><topic>Transforming Growth Factor alpha - genetics</topic><topic>Vertebrata</topic><topic>Zinc Fingers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barrow, Lon L.</creatorcontrib><creatorcontrib>Simin, Karl</creatorcontrib><creatorcontrib>Jones, Julie M.</creatorcontrib><creatorcontrib>Lee, David C.</creatorcontrib><creatorcontrib>Meisler, Miriam H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Genomics (San Diego, Calif.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barrow, Lon L.</au><au>Simin, Karl</au><au>Jones, Julie M.</au><au>Lee, David C.</au><au>Meisler, Miriam H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conserved Linkage of Early Growth Response 4, Annexin 4, and Transforming Growth Factor α on Mouse Chromosome 6</atitle><jtitle>Genomics (San Diego, Calif.)</jtitle><addtitle>Genomics</addtitle><date>1994-01-15</date><risdate>1994</risdate><volume>19</volume><issue>2</issue><spage>388</spage><epage>390</epage><pages>388-390</pages><issn>0888-7543</issn><eissn>1089-8646</eissn><abstract>The mouse genes encoding early growth response 4 (Egr4), annexin IV (Anx4), and transforming growth factor a (Tgfa) have been mapped to a linkage group on mouse chromosome 6 that is conserved on human chromosome 2p11-p13. The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa and 1/215 recombinants between these genes and Egr4 . The genes are located approximately 2 cM distal to mnd2, a mouse mutation causing neuromuscular disease. The results demonstrate that mnd2 is located at an internal position within this conserved linkage group.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>8188273</pmid><doi>10.1006/geno.1994.1078</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Genomics (San Diego, Calif.), 1994-01, Vol.19 (2), p.388-390 |
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| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Annexin A4 - genetics Biological and medical sciences Chromosome Mapping Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Genes Genetic Linkage Genetics of eukaryotes. Biological and molecular evolution Humans Mice - genetics Neuromuscular Diseases - genetics Recombination, Genetic Transcription Factors - genetics Transforming Growth Factor alpha - genetics Vertebrata Zinc Fingers |
| title | Conserved Linkage of Early Growth Response 4, Annexin 4, and Transforming Growth Factor α on Mouse Chromosome 6 |
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