The relationship between 17β hydroxysteroid dehydrogenase and breast tumour site and size

The activity of 17β hydroxysteroid dehydrogenase (17OHSD) was measured in adipose tissue adjacent to benign or malignant breast tumours. 17OHSD activity was signficantly correlated with tumour size in malignant tumours (r = 0.75) but not with benign tumours (r = 0.28). Enzyme activity was reduced in...

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Veröffentlicht in:International journal of cancer 1985-12, Vol.36 (6), p.685-687
Hauptverfasser: Beranek, P. A., Folkerd, E. J., Newton, C. J., Reed, M. J., Ghilchik, M. W., James, V. H. T.
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Sprache:eng
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Zusammenfassung:The activity of 17β hydroxysteroid dehydrogenase (17OHSD) was measured in adipose tissue adjacent to benign or malignant breast tumours. 17OHSD activity was signficantly correlated with tumour size in malignant tumours (r = 0.75) but not with benign tumours (r = 0.28). Enzyme activity was reduced in adipose tissue adjacent to tumours obtained from inferior breast quadrants.
ISSN:0020-7136
1097-0215
DOI:10.1002/ijc.2910360611