Effect of phenoxymethylpenicillin and erythromycin prophylaxis on anaerobic bacteraemia after oral surgery

The effect of antibiotic prophylaxis on bacteraemia was assessed in 60 oral surgery operations. Fifty-one patients were divided in three groups receiving a 2 g dose of phenoxymethylpenicillin, a 0·5 g dose of erythromycin or no prophylaxis. During operation, the total numbers of bacteria were lower...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1985-08, Vol.16 (2), p.243-251
Hauptverfasser:	Josefsson, Kenneth, Heimdahl, Anders, von Konow, Lars, Nord, Carl Erik
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria, Anaerobic - drug effects Biological and medical sciences Erythromycin - blood Erythromycin - therapeutic use Female Humans Male Medical sciences Microbial Sensitivity Tests Middle Aged Molar, Third - surgery Penicillin V - blood Penicillin V - therapeutic use Pharmacology. Drug treatments Premedication Saliva - microbiology Sepsis - prevention & control Tooth Extraction Tooth, Impacted - surgery
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Zusammenfassung:	The effect of antibiotic prophylaxis on bacteraemia was assessed in 60 oral surgery operations. Fifty-one patients were divided in three groups receiving a 2 g dose of phenoxymethylpenicillin, a 0·5 g dose of erythromycin or no prophylaxis. During operation, the total numbers of bacteria were lower in the antibiotic groups than in the non-treatment groups (P
ISSN:	0305-7453 1460-2091
DOI:	10.1093/jac/16.2.243