Competitive in situ hybridization in a mediastinal germ cell tumor
We performed competitive in situ hybridization in a mediastinal germ cell tumor to identify chromosome 12 aberration(s). DNA from a mouse-human somatic hybrid cell line, containing an i(12p) as unique human material, was labeled and used as a probe. Our results confirm that the chromosome marker, ob...
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| Veröffentlicht in: | Cancer genetics and cytogenetics 1994-03, Vol.73 (1), p.53-56 |
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| container_title | Cancer genetics and cytogenetics |
| container_volume | 73 |
| creator | Sayed Aly, Magdy Dal Cin, Paola Jiskoot, Peter Deneffe, Georges Marynen, Peter Van den Berghe, Herman |
| description | We performed competitive in situ hybridization in a mediastinal germ cell tumor to identify chromosome 12 aberration(s). DNA from a mouse-human somatic hybrid cell line, containing an i(12p) as unique human material, was labeled and used as a probe. Our results confirm that the chromosome marker, observed in mediastinal germ cell tumor and cytogenetically identified as i(12p), is a true isochromosome of the short arm of chromosome 12. |
| doi_str_mv | 10.1016/0165-4608(94)90181-3 |
| format | Article |
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DNA from a mouse-human somatic hybrid cell line, containing an i(12p) as unique human material, was labeled and used as a probe. 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DNA from a mouse-human somatic hybrid cell line, containing an i(12p) as unique human material, was labeled and used as a probe. 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Dal Cin, Paola ; Jiskoot, Peter ; Deneffe, Georges ; Marynen, Peter ; Van den Berghe, Herman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-449175e8363a3aa5176f14cdefe03c860a70261b4a08ff5d3bde8a7edcb1c2883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adolescent</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>chromosome 12</topic><topic>Chromosome Aberrations</topic><topic>Chromosome Banding</topic><topic>Chromosome Disorders</topic><topic>Chromosomes, Human, Pair 12</topic><topic>germ cells</topic><topic>Germinoma - genetics</topic><topic>Germinoma - pathology</topic><topic>Germinoma - therapy</topic><topic>Humans</topic><topic>Hybrid Cells</topic><topic>In Situ Hybridization - methods</topic><topic>inversion</topic><topic>Male</topic><topic>man</topic><topic>Mediastinal Neoplasms - genetics</topic><topic>Mediastinal Neoplasms - pathology</topic><topic>Mediastinal Neoplasms - therapy</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Pneumology</topic><topic>tumors</topic><topic>Tumors of the respiratory system and mediastinum</topic><toplevel>online_resources</toplevel><creatorcontrib>Sayed Aly, Magdy</creatorcontrib><creatorcontrib>Dal Cin, Paola</creatorcontrib><creatorcontrib>Jiskoot, Peter</creatorcontrib><creatorcontrib>Deneffe, Georges</creatorcontrib><creatorcontrib>Marynen, Peter</creatorcontrib><creatorcontrib>Van den Berghe, Herman</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Human Genome Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer genetics and cytogenetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sayed Aly, Magdy</au><au>Dal Cin, Paola</au><au>Jiskoot, Peter</au><au>Deneffe, Georges</au><au>Marynen, Peter</au><au>Van den Berghe, Herman</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Competitive in situ hybridization in a mediastinal germ cell tumor</atitle><jtitle>Cancer genetics and cytogenetics</jtitle><addtitle>Cancer Genet Cytogenet</addtitle><date>1994-03-01</date><risdate>1994</risdate><volume>73</volume><issue>1</issue><spage>53</spage><epage>56</epage><pages>53-56</pages><issn>0165-4608</issn><eissn>1873-4456</eissn><coden>CGCYDF</coden><abstract>We performed competitive in situ hybridization in a mediastinal germ cell tumor to identify chromosome 12 aberration(s). DNA from a mouse-human somatic hybrid cell line, containing an i(12p) as unique human material, was labeled and used as a probe. Our results confirm that the chromosome marker, observed in mediastinal germ cell tumor and cytogenetically identified as i(12p), is a true isochromosome of the short arm of chromosome 12.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8174074</pmid><doi>10.1016/0165-4608(94)90181-3</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0165-4608 |
| ispartof | Cancer genetics and cytogenetics, 1994-03, Vol.73 (1), p.53-56 |
| issn | 0165-4608 1873-4456 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Animals Biological and medical sciences chromosome 12 Chromosome Aberrations Chromosome Banding Chromosome Disorders Chromosomes, Human, Pair 12 germ cells Germinoma - genetics Germinoma - pathology Germinoma - therapy Humans Hybrid Cells In Situ Hybridization - methods inversion Male man Mediastinal Neoplasms - genetics Mediastinal Neoplasms - pathology Mediastinal Neoplasms - therapy Medical sciences Mice Pneumology tumors Tumors of the respiratory system and mediastinum |
| title | Competitive in situ hybridization in a mediastinal germ cell tumor |
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