Leukocyte response to administration of corticosteroid in healthy black children with neutropenia

After a challenge with corticosteroid, increments in the absolute neutrophil count were >50% in eight healthy black children with neutropenia, and >2.0 × 109/L (>2000/mm3) in all but one child. Decrements in the absolute lymphocyte count mirrored the increments. Stimulation with hydrocortis...

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Veröffentlicht in:	The Journal of pediatrics 1994-05, Vol.124 (5), p.739-741
Hauptverfasser:	Haddy, Theresa B., Rana, Sohail R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent African Continental Ancestry Group Biological and medical sciences Case-Control Studies Child Child, Preschool Drug toxicity and drugs side effects treatment Female Humans Hydrocortisone - pharmacology Infant Leukocyte Count - drug effects Lymphocytes - drug effects Male Medical sciences Neutropenia - blood Neutropenia - ethnology Neutropenia - immunology Neutrophils - drug effects Pharmacology. Drug treatments Reference Values Toxicity: blood
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Zusammenfassung:	After a challenge with corticosteroid, increments in the absolute neutrophil count were >50% in eight healthy black children with neutropenia, and >2.0 × 109/L (>2000/mm3) in all but one child. Decrements in the absolute lymphocyte count mirrored the increments. Stimulation with hydrocortisone may be useful in characterizing ethnic neutropenia. (J PEDIATR 1994;124:739-41)
ISSN:	0022-3476 1097-6833
DOI:	10.1016/S0022-3476(05)81366-6