Human Mycoses: Drugs and Targets for Emerging Pathogens

Fungal infections have increased dramatically since 1974, and new approaches and chemicals for treating fungal infections are desperately needed. The three major groups of antifungal compounds in clinical use are described.

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Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1994-04, Vol.264 (5157), p.371-373
Hauptverfasser:	Georgopapadakou, Nafsika H., Walsh, Thomas J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterials Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Antifungals Azoles Biological and medical sciences Cell membranes Cell Wall - drug effects Chitin Composition Death Delivery Systems DNA Drug therapy Ergosterol - metabolism Fungal infections Fungi Fungi - drug effects Fungi - metabolism Humans Infections Medical sciences Mycoses Mycoses - drug therapy Mycoses - microbiology Narcotics Pathogens Patients Perspectives Pharmacology. Drug treatments Squalene
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Beschreibung
Zusammenfassung:	Fungal infections have increased dramatically since 1974, and new approaches and chemicals for treating fungal infections are desperately needed. The three major groups of antifungal compounds in clinical use are described.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.8153622