A study of the mediator spectrum of Δ-9 tetrahydrocanabinol effects on cerebral bioelectric activity

Defense conditioning in cats with simultaneous recording of bioelectric activity was used to show that serotonin-negative and dopamine-positive substances normalize Δ-9 THC-elicited dissimilarity of amplitudinal and temporal parameters of evoked potentials in visual associative and somatosensoric zo...

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Veröffentlicht in:Drug and alcohol dependence 1985-08, Vol.15 (4), p.383-388
Hauptverfasser: Machula, A.I., Barkov, N.K.
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Barkov, N.K.
description Defense conditioning in cats with simultaneous recording of bioelectric activity was used to show that serotonin-negative and dopamine-positive substances normalize Δ-9 THC-elicited dissimilarity of amplitudinal and temporal parameters of evoked potentials in visual associative and somatosensoric zones II of the cerebral cortex. It was also found that serotoninergic substances affect both primary and secondary waves of evoked potentials while dopaminergic substances influence only late waves.
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Animals
Apomorphine - pharmacology
Cathecholamines
Cats
Cerebral Cortex - drug effects
Conditioning (Psychology) - drug effects
Dopamine
Dopamine - metabolism
Dronabinol - pharmacology
Electroencephalography
Evoked potentials
Evoked Potentials, Visual - drug effects
Fenclonine - pharmacology
Levodopa - pharmacology
Methyltyrosines - pharmacology
Methysergide - pharmacology
Norepinephrine - metabolism
Serotonin
Serotonin - metabolism
Somatosensory Cortex - drug effects
Sympathomimetics - pharmacology
Visual Cortex - drug effects
Visual differentiation
Δ-9 Tetrahydrocanabinol
title A study of the mediator spectrum of Δ-9 tetrahydrocanabinol effects on cerebral bioelectric activity
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