A study of the mediator spectrum of Δ-9 tetrahydrocanabinol effects on cerebral bioelectric activity

Defense conditioning in cats with simultaneous recording of bioelectric activity was used to show that serotonin-negative and dopamine-positive substances normalize Δ-9 THC-elicited dissimilarity of amplitudinal and temporal parameters of evoked potentials in visual associative and somatosensoric zones II of the cerebral cortex. It was also found that serotoninergic substances affect both primary and secondary waves of evoked potentials while dopaminergic substances influence only late waves.