A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes
Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridi...
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Veröffentlicht in: | Chromosoma 1985-01, Vol.92 (5), p.369-377 |
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creator | Mitchell, A R Gosden, J R Miller, D A |
description | Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed. |
doi_str_mv | 10.1007/bf00327469 |
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It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. 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The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed.</description><subject>Base Sequence</subject><subject>Centromere - ultrastructure</subject><subject>Chromosomes - ultrastructure</subject><subject>Chromosomes, Human - ultrastructure</subject><subject>Cloning, Molecular</subject><subject>DNA - genetics</subject><subject>DNA Restriction Enzymes</subject><subject>DNA Transposable Elements</subject><subject>Escherichia coli - genetics</subject><subject>Humans</subject><subject>Hybrid Cells - cytology</subject><subject>Male</subject><subject>Nucleic Acid Hybridization</subject><subject>Repetitive Sequences, Nucleic Acid</subject><subject>Spermatozoa</subject><issn>0009-5915</issn><issn>1432-0886</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkb1PwzAQxS0EKqWwsCN5YkAN2E7ij7GUjyJVsMAcOfZZKUriYCdD_3tSWliZTnf3uye9ewhdUnJLCRF3pSMkZSLj6ghNaZayhEjJj9GUEKKSXNH8FJ3F-LlrGScTNGFKcZnlU9QssKl9CxZH-BqgNTDHnWSrOfYO9xVgXXeV31gcoAPdj9zD6wI73WzqLXZ-aC3W_Q9ooO2DbyBA3N3qusbV0OgWm2oc-ziu4jk6cbqOcHGoM_Tx9Pi-XCXrt-eX5WKdmFSoPrEltSWUIlMMjBXa5dSCMyJ3CqSyUph89JGRVDrLHGcGOFcut9o4Rw216Qxd73W74EdXsS-aTTRQ17oFP8RC8IwxJfN_QZoxLoVSI3izB03wMQZwRRc2jQ7bgpJiF0Jx__QbwghfHVSHsgH7hx6-nn4Dz3yCUw</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>Mitchell, A R</creator><creator>Gosden, J R</creator><creator>Miller, D A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19850101</creationdate><title>A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes</title><author>Mitchell, A R ; Gosden, J R ; Miller, D A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c379t-db1dbeb7492ecd7af51defc75f9e89d87c59264038fd2f62ce669f5dacff1c1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Base Sequence</topic><topic>Centromere - ultrastructure</topic><topic>Chromosomes - ultrastructure</topic><topic>Chromosomes, Human - ultrastructure</topic><topic>Cloning, Molecular</topic><topic>DNA - genetics</topic><topic>DNA Restriction Enzymes</topic><topic>DNA Transposable Elements</topic><topic>Escherichia coli - genetics</topic><topic>Humans</topic><topic>Hybrid Cells - cytology</topic><topic>Male</topic><topic>Nucleic Acid Hybridization</topic><topic>Repetitive Sequences, Nucleic Acid</topic><topic>Spermatozoa</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mitchell, A R</creatorcontrib><creatorcontrib>Gosden, J R</creatorcontrib><creatorcontrib>Miller, D A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chromosoma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mitchell, A R</au><au>Gosden, J R</au><au>Miller, D A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes</atitle><jtitle>Chromosoma</jtitle><addtitle>Chromosoma</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>92</volume><issue>5</issue><spage>369</spage><epage>377</epage><pages>369-377</pages><issn>0009-5915</issn><eissn>1432-0886</eissn><abstract>Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. 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subjects | Base Sequence Centromere - ultrastructure Chromosomes - ultrastructure Chromosomes, Human - ultrastructure Cloning, Molecular DNA - genetics DNA Restriction Enzymes DNA Transposable Elements Escherichia coli - genetics Humans Hybrid Cells - cytology Male Nucleic Acid Hybridization Repetitive Sequences, Nucleic Acid Spermatozoa |
title | A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes |
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