Spurious assessment of acid-base status due to dilutional effect of heparin

A patient was encountered in whom clinically significant spurious hypocapnia and hypobicarbonatemia were diagnosed resulting from the dilutional effect of excessive amounts of sodium heparin solution in the blood sample. This report presents the relevant data in this patient, summarizes the effects...

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Veröffentlicht in:	The American journal of medicine 1985-10, Vol.79 (4), p.528-530
Hauptverfasser:	Bloom, Stephen A., Canzanello, Vincent J., Strom, James A., Madias, Nicolaos E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid-Base Imbalance - diagnosis Aged Analysis Bicarbonates - blood Biological and medical sciences Blood Specimen Collection - methods Carbon Dioxide - blood General pharmacology Heparin Humans Hydrogen-Ion Concentration Male Medical sciences Pharmacology. Drug treatments
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Beschreibung
Zusammenfassung:	A patient was encountered in whom clinically significant spurious hypocapnia and hypobicarbonatemia were diagnosed resulting from the dilutional effect of excessive amounts of sodium heparin solution in the blood sample. This report presents the relevant data in this patient, summarizes the effects of heparin on the determination of the acid-base status, and provides suggestions for avoiding this important pitfall in clinical practice.
ISSN:	0002-9343 1555-7162
DOI:	10.1016/0002-9343(85)90044-0